Welcome to the Laboratory of Dr. John T. Harty, Ph.D., in the University of Iowa's Department of Microbiology and Immunology. We are also associated with the Department of Pathology, the Interdisciplinary Graduate Program in Immunology, and the Cancer Center at the University of Iowa College of Medicine.

Research in the Harty laboratory is focused on understanding the dynamics of the T cell response, how effector and memory T cell differentiation are regulated, how memory T cell populations are maintained and how they can be generated and manipulated to enhance protective immunity.

Lab Photo, Summer of 2019

Congratulations to our new postdoc Lisa Drewry on the publication of her graduate work, out in Nature Microbiology:

The secreted kinase ROP17 promotes Toxoplasma gondii dissemination by hijacking monocyte tissue migration

Speech! (Sam Kurup's farewell party)
Dr. Samarchith Kurup left us to start his career as a faculty member in Athens at the Center for Tropical & Emerging Global Diseases at the University of Georgia. We are all sad to lose Sam, and wish him and his lovely family well!

Dr. Lisa Drewry and Dr. Stephanie van de Wall joined us in the summer of 2019 as Postdocs.  Welcome! 

Nature Medicine Volume 23 No 10 October 2017
Research from our lab was featured on the cover of Nature Medicine. The cover image depicts a germinal-center reaction in the spleen of a mouse infected with Plasmodium yoelii, after treatment with anti-CTLA-4. CD4+ T helper cells (green), B cells (blue), germinal-center B cells (white) and plasmablasts (red) are shown. Image credit: Dr. Samarchith P. Kurup and the University of Iowa Central Microscopy Research Facility. Artwork by Erin Dewalt.

Congratulations to Dr. Scott Anthony for being named the 2019 Lefrançois-BioLegend Award Recipient at the 2019 AAI Meeting. Established to honor the memory of AAI member Leo Lefrançois, Ph.D., this award is intended to advance the career of a trainee (graduate student or postdoctoral fellow) who attends the AAI annual meeting and presents an outstanding abstract specifically in the area of mucosal immunology. This award is generously supported by BioLegend and donations from friends and colleagues of Dr. Lefrançois.

New Review: T cell-mediated immunity to malaria

New Paper: Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria

Congratulations to Dr. Stina Urban for being named a 2018-2019 AAI Public Policy Fellow http://www.aai.org/Alerts/Public_Affairs/2018/2018-19-fellows-announced.html


Mitchell Lefebvre, MSTP Student
Congratulations to our MSTP student, Mitchell Lefebvre, on the publication of his Trends in Parasitology review "You Shall Not Pass: Memory CD8 T Cells in Liver-Stage Malaria" (Free download through Mid-February)