John T. Harty Laboratory at the University of Iowa
Welcome to the Laboratory of Dr. John T. Harty, Ph.D., in the University of Iowa's Department of Pathology. We are also associated with the Interdisciplinary Graduate Program in Immunology, and the Cancer Center at the University of Iowa College of Medicine.
Research in the Harty laboratory is focused on understanding the dynamics of the T cell response, how effector and memory T cell differentiation are regulated, how memory T cell populations are maintained and how they can be generated and manipulated to enhance protective immunity.
Career and Publication Announcements
Congratulations to Harty Lab alumnus Ali Jabbari, MD, PhD, who has been appointed the chair and departmental executive officer of the Department of Dermatology in the University of Iowa Roy J. and Lucille A. Carver College of Medicine! Details here. Dr. Jabbari's current research involves autoimmune mechanisms and immunoregulatory circuits in relation to the hair follicle.
Congratulations to Harty Lab alumnus Noah Butler, PhD, who was promoted to Full Professor in the Department of Microbiology at the University of Iowa. Check out the Butler Webpage for more details on Dr. Butler's work and associations.
New invited review: Memory CD8+ T cell-mediated protection against liver-stage malaria co-authored by Dr. Mariah Hassert and Sahaana Arumugam (Immunol Rev. 2023; 00: 1- 20)
New Paper Alert! Dr. Lisa Drewry and Dr. Stephanie van de Wall (and more)'s new paper is available online ahead of print:
CD4 T Cell-Dependent and -Independent Roles for IFN-γ in Blood-Stage Malaria in J Immunol 2023 Mar 20
Congratulations to Dr. Mitchell LeFebvre on beginning the next phase of his Medical Science Training at Yale University Dermatology!
Congratulations to Dr. Mariah Hassert on her NIH F32 Postdoctoral Fellowship
Congratulations to Dr. van de Wall and former Masters student Sequoia Crooks on the publication of their newest Cutting Edge article in JI
Dr. Lisa Drewry has started at Vir Biotechnology! The best of luck to her!
A warm welcome to our newest rotation student, Payton Kahl
Madison Mix's newest article is available online now! Click here for free access Trends in Immunology
Congratulations to Dr. Hassert on the publication of her perspective article in Frontiers in Immunology
A warm welcome to our newest MSTP student, Sahaana Arumugam!
Congratulations to new mom Dr. Lisa Drewry!
Congratulations to our MSTP & Immunology Graduate student Madison R. Mix as a recipient of the Graduate College Post-Comprehensive Research Fellowship for Fall 2022!
Congratulations to our MSTP student Dr. Mitchell Lefebvre, who successfully defended his Ph.D. on Monday (12/6/21)!
A big welcome to our newest Postdoc, Mariah Hassert, joining us from Saint Louis University this August!
Congratulations to our own Sequoia Crooks for her successful MS thesis defense on 7/14/21!
Dr. Scott Anthony has also left us to join the Integrated Research Facility at National Institute of Allergy and Infectious Diseases (NIAID) on the east coast. Good luck to him as well!
Dr. Stina Urban has left us to join Pfizer out on the west coast. Best of luck to her in her new career!
Dr. Lisa Drewry's newest paper is available with a free access link (through 9/3/20): RPL-6: An Achilles Needle in the Malaria Haystack?
Dr. Stina Urban's newest paper is now online ahead of print in Nature Immunology https://www.nature.com/articles/s41590-020-0711-8
Congratulations to our alum Dr. Martin Richer who is now a tenured Associate Professor at McGill! Check out his research here: https://www.mjricherlab.com
Update: The Richer lab will be moving to the Department of Microbiology and Immunology at the Indiana University School of Medicine in Indianapolis in September.
The Harty lab moved to the Department of Pathology as of May 2020. Thank you to all our former and current colleagues in Microbiology and Immunology for their support and we wish them the best of luck going forward!
Congratulations to our new postdoc Lisa Drewry on the publication of her graduate work, out in Nature Microbiology:
The secreted kinase ROP17 promotes Toxoplasma gondii dissemination by hijacking monocyte tissue migration
Dr. Samarchith Kurup left us to start his career as a faculty member in Athens at the Center for Tropical & Emerging Global Diseases at the University of Georgia. We are all sad to lose Sam, and wish him and his lovely family well!
Research from our lab was featured on the cover of Nature Medicine. The cover image depicts a germinal-center reaction in the spleen of a mouse infected with Plasmodium yoelii, after treatment with anti-CTLA-4. CD4+ T helper cells (green), B cells (blue), germinal-center B cells (white) and plasmablasts (red) are shown. Image credit: Dr. Samarchith P. Kurup and the University of Iowa Central Microscopy Research Facility. Artwork by Erin Dewalt.
Congratulations to Dr. Scott Anthony for being named the 2019 Lefrançois-BioLegend Award Recipient at the 2019 AAI Meeting. Established to honor the memory of AAI member Leo Lefrançois, Ph.D., this award is intended to advance the career of a trainee (graduate student or postdoctoral fellow) who attends the AAI annual meeting and presents an outstanding abstract specifically in the area of mucosal immunology. This award is generously supported by BioLegend and donations from friends and colleagues of Dr. Lefrançois.
New Review: T cell-mediated immunity to malaria
Congratulations to Dr. Stina Urban for being named a 2018-2019 AAI Public Policy Fellow http://www.aai.org/Alerts/Public_Affairs/2018/2018-19-fellows-announced.html
Dr. Harty was please to give the 2023 Ingraham Lecture at the Indiana University School of Medicine Department of Microbiology & Immunology this past week. He was hosted by former postdocs Dr. Martin Richer and Dr. Nathan Schmidt. Photo credit: Dr. Mark Kaplan
Dr. Hassert's News & views article Alt-RNAtive vaccines elicit anti-malarial TRM cells has been published online in Nature Immunology (full-text access to a view-only version)
A big welcome to our newest Postdoctoral Fellow, Cori Fain! Dr. Fain joins us from the Immunology program at the Mayo Clinic, where she focused on neuro-immunology.